The US CFTC stated that it will "respect the opinions of all sports leagues," following the NFL's call for stronger regulation of the prediction market.

CoinFeed reported on March 31 that, according to The Block, Michael Selig, Chairman of the U.S. Commodity Futures Trading Commission (CFTC), stated that the agency will "largely respect the opinions of sports leagues" when assessing which prediction market contracts are susceptible to manipulation. Previously, the National Football League (NFL) sent letters to prediction market platforms such as Kalshi and Polymarket, demanding they cease offering contracts for single-game results, drafts, injuries, and other easily manipulated or pre-determined information, arguing that such contracts could induce manipulation. On the legislative front, bipartisan lawmakers have introduced bills to prohibit federally regulated prediction markets from listing sports-related contracts, and several states have also challenged the legality of these platforms through legal channels. Meanwhile, Major League Baseball (MLB) has opted for a collaborative approach, partnering with Polymarket and signing an information-sharing agreement.